The Secret Link: Your Gut Brain Connection

Dr Will Cole the gut brain connection

In this podcast episode, I'm talking with Dr. Will Cole about the, gut brain connection, and how your gut feelings, can affect your brain. Dr. Cole is a world-renowned functional medicine practitioner and health advisor to Gwyneth Paltrow. He is an expert in the field of, cellular health, and inflammation, and he has some amazing insights to share with you about the connection between how you eat and how you feel. If you're curious about the, gut brain connection, and how your, gut feelings, can affect your overall health, then this podcast episode is for you! Dr. Cole discusses the relationship between your gut and brain in detail and explains how you can use this knowledge to improve your health and well-being.

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The gut-brain connection explained

Dr Will Cole Health advisor to Gwyneth Paltrow top functional medicine practitioner in New York Times best-selling author has dedicated his career to teaching people to apply skepticism to National Trends and instead pay closer attention to their own intuition his new book “Gut Feelings Healing the Shame Fueled Relationship Between What you Eat and What you Feel” and how you feel sorry demystifies the gut brain connection and provides a framework to prepare the relationship between what you eat and how you feel .

Named one of the top 50 functional and integrated doctors in the nation Dr Will Cole provides a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances ,digestive disorders, and brain problems. He's the host of “Art of the Being Well” podcast and the author of ” Ketotarian the Information Spectrum” and the New York Times bestseller “Intuitive Fasting”

Myrna: I have followed you for years on Instagram and Facebook but a few months ago you know I'm always on YouTube I have a YouTube channel so I saw your Ad about, cellular health, and I thought it was so great that I wanted to sign up for the webinar on autoimmune conditions and cellular inflammation.  I signed up for your, health assessment, where they sent me a kit to check my inflammation levels.

Can you introduce yourself by telling our audience um you know how you became to be one of the top 50 functional medicine doctors the doctor of Gwyneth Paltrow and maybe you can introduce us to what you do with helping clients get rid of their, cellular inflammation.

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Functional medicine and Telehealth

Dr Cole: we've been in Telehealth for the 13 for 13 plus years like that's been our day job and my passion and my heart is to really be a part of people's Health journey and figure out why they're struggling with their health issues right so that's our main focus and from that the passion and that sacred responsibility that I hold for our Telehealth patients comes the books in the podcast like all of that Springs from that so thank you for I honor I'm honestly honored that you have to be a part of your health journey and I take that extremely seriously and as I mentioned like we've we started within the first functional medicine Telehealth centers 13 plus years ago

We have several ways that we serve Telehealth patients we have our one-on-one Telehealth concierge which is one-on-one private sessions, and then we have the, autoimmune Health reset, that we launched years ago like three years ago at this point to enhance or  level up the amount of people we can support.   The urine test reveals inflammation which  is the commonality between just about every health problem Under the Sun.

Inflammation and insulin resistance

I mean autoimmune problems are inflammatory metabolic issues like trouble losing weight, insulin resistance, type 2 diabetes, PCOS polycystic ovarian syndrome, which is driven by, insulin resistance, and other hormonal problems to digestive problems you mentioned musculoskeletal inflammation issues to even things like fatigue and anxiety and depression are all inflammatory there's a whole field of research called the cytokine model of cognitive function cytokines are pro-inflammatory cells.

Researchers exploring in the scientific literature how does inflammation impact how our brain works. How does inflammation impact mental health so what one of the ways we measure inflammation is that urine tests, but we also run blood tests like high sensitivity C-reactive protein homocysteine levels. These are just objective data points to show people their Baseline.   What's driving the inflammation in both physiological and psychological components is underlying, gut health.

75 percent of your, immune system, resides so there's a lot of gut-centric components to inflammation that could impact your joints, going to impact your mental health it could impact your hormones and impact your blood sugar that we need to calm down so what you embarked on through that group Telehealth model was us to calm down these root causes of inflammation so people can live the life they were created for.

Also natural medicines biohacking different tools mind-body practices trauma work to really deal with what's causing that dysregulation of their immune system which is what chronic inflammation is.  Inflammation is not inherently bad, it's a product of the immune system.

Gut brain connection and the vagus nerve

Myrna: I've always known about the, gut brain connection, and the, leaky gut, but I've been learning specifically about you know things getting through the lining and causing inflammation and and I see now where you know the gut is the main resource which is mitochondria and all these different things.  Can you talk about the, gut brain connection.

Dr Cole:  I mentioned that inflammation is a product of the immune system 75 % to about two-thirds of the immune system resides in the gut or originates in the gut so to understand inflammation you want to look at where the predominance of the immune system resides. But not just from an immune inflammatory standpoint, but also from a, brain health ,standpoint. The gut and brain are actually formed from the same fetal tissue so when babies are growing in their mother's womb the gut and brain are formed .

Serotonin a neurotransmitter is made in the gut and stored in the gut.  Fifty percent of dopamine, the pleasure neurotransmitter is made and stored in the gut.  The vagus nerve which is the largest cranial nerve in the body these neurotransmitters as we understand it today are made in the gut don't pass through the blood-brain barrier but what they do is crosstalk to the brain through the vagus nerve.

Parasympathetic response and the vagus nerve

So when you hear these conversations that are happening more and more around a dysregulated nervous system what we're actually talking about here is an overactive sympathetic state of that fight, flight or freeze stressed inflamed State and an under active parasympathetic that resting digesting hormone balance date both are important just like inflammation there's nothing inherently wrong with the sympathetic response it's meant to protect that us and it does protect us but it's meant to come up and overact and then calm down when the threat is removed.

Most people are in a state of nervous system dysregulation that it's just always on the sympathetic response is always on to varying degrees and that as you're an underactive resting digesting meaning calm anti-anxiety normal, gut health, normal digestive response. This has to do with what's called the nervous system it's the neuro-aminoendocrine axis so the intersection between our nervous system the endocrine system.

Myrna:  How does the gut influence your hormone production or depression? Can you bridge the gap on inflammation as the commonality between all these health problems?

Dr Cole: But the word there the key word is commonality meaning it's the common link but something's causing the inflammation so what's Upstream to the inflammation because if inflammation's not inherently bad we're just talking about dysregulated chronic inflammation, that forest fire that's burning perpetuity for people that's impacting their mental health and their physical health and their hormones and their digestion and their pain levels and their energy levels.

We look at what's causing the inflammation.  It's like the check engine light, so if the check engine light's on in your car you don't just keep under driving and cover up the check engine light and act like it's not on.  Let's do some Diagnostics to see why that check engine light is on, so that's what we do in functional medicine. So I talk about this in the book at both physiological and psychological drivers of inflammation, so both approaches have to be looked at.

Gut Feelings: The gut brain connection

So underlying gut problems nutrient deficiencies chronic infections like we deal with mold toxicity or chronic lyme disease or environmental toxins those physiological things will impact inflammation, impact our mood and all that stuff it can impact the anxiety depression automate everything on the psychological side.   The Chronic infections environmental toxins will can trigger that for some people that have genetic predispositions for autoimmunity, but on a psychological thing side of things.

That's why in part why I called the book, gut feelings, it's gut and feelings it's a physiological and the psychological the physical and the mental emotional spiritual.  Those things can trigger the, gut brain connection, things like unresolved trauma and chronic stress and something that I call in the book shame formation. Because our body is a cellular library and our thoughts and our words our emotions our experiences will impact the expression of our biochemistry.

Myrna:  I've had several um people on the show talk about childhood trauma results in autoimmune conditions so I'm getting the connection now so that's amazing.

Alcohol and the gut brain connection

Myrna: You say that alcohol affects our, gut brain connection.  Are you including red wine as alcohol?

Dr Cole: I'm including red wine in this bucket, so you could make the argument that there's some Redemptive qualities for wine right because it has it Resveratrol which is like antioxidant yeah so you know and it has like polyphenols like other antioxidants in it because it's from like the grapes that is true but actually this compelling amount of data that shows you need to drink an obscene amount of wine to get like to a great therapeutic dose.

Now you can make the other argument towards alcohol and say well couldn't it be alcohol is a hormetic effect in the body it's like a hormesis is a term that means like a good stressor on the body that makes the cells more resilient so fasting is a harmonic effect high intensity interval training is a hermetic effect cold therapy sauna these are all hormatic effects in the body.   Let's do some high intention interval training, that's healthier forms of hermesis than this alcohol .  Then supplement with Resveratrol or drink some eat some fruits and vegetables.

Myrna:  I've heard time and time again about the benefits of red wine my husband is an avid Red Wine Drinker and I just picked it up again like a couple weeks ago because because I heard about the benefits of red wine.

Dr Cole:  I need to talk to your husband .

Myrna:  So you have a 21 day gut feeling plan designed to help your clients heal can you talk to us about that what's in that plan.

Dr Cole:   I adapted the plan in the book based off of different tools that we Implement into our Telehealth patients  lives into their protocols so for this book every day of the 21 days there's a gut and a Feeling tool. So there's a physiological and a psychological gut day.  We could do a little bit of what you did during that autoimmune Health reset, we focus on soups and stews which is a great way to support that ,gut brain access, that microbiome mood axis to also lower inflammations, which is where two-thirds of the immune system resides.

So this is nothing new to our Landscapes humans right you look at any traditional Society they use soups and stews lots of times right I mean just every day let alone when somebody's sick or therapeutically you know that cliche of chicken noodle soup it's not the noodles that we're helping people it was the broths and the vegetables that were cooked down it was the proteins that were cooked and easy to digest so there's something healing about that on many levels for people.

So it's born as a protocol that we we modify for patients based on what's relevant to them we modify what's called a gaps protocol a it's an acronym gaps it stands for gut and psychology syndrome or gut and Physiology syndrome which is the gut brain Axis or the gut immune Axis or like chronic autoimmune problems so it's used clinically with different applications for different purposes. So I  give soup recipes and broth recipes in the book to support that, gut brain immune access, over the course of the 21 days.

On the feelings  side, my favorite science back tools that I've seen really work in patients lives also the research is so exciting so things like breath work and the history of breath work and breath work practices that helps to regulate the nervous system, strengthening the vagal tone. A lot of the plan is actually improving vagal tone, most people have a weak vagus nerve they're resting digesting the system is weak they have anxiety inflammation and poor digestion.

We're actually helping to support and strengthen so food on the physiological side on the gut side of that, gut feeling, crosstalk will help to improve vagal tone because the more you lower inflammation the more you support gut from gut health from a nutrition standpoint will improve vagal tone but on a psychological side we need to implement things like breath work to strengthen the vagus nerve to regulate that nervous system.

Strengthening the vagus nerve

Myrna:  I do a lot of meditation on the vagus nerve because  everything happens when you relax and that is one way I help myself relax and I do you know breath work meditation,  I wasn't aware that you can strengthen the vagus nerve so this is new information for me.

Myrna: Your  book Gut Feelings: Healing the Shame-Fueled Relationship Between What You Eat and How You Feel is on Amazon so tell us how people can get in contact with you your website social media

Dr Cole:  Everything's at Drwillcole.com  all the links to everything we talked about in today's conversation are there, so are the links to the Telehealth Center.  We have new Telehealth patient options now open a the autoimmune Health reset is one of them but lab information people can run Labs. The links to the books are there Gut Feelings,  Intuitive fasting, The inflammation spectrum and Ketotarian the links to the podcast The Art of Being Well. I have a new episode every week. I'm on Instagram @Drwillcole same with Facebook Tic Tock.

Additional Resources

What is the Connection Between Childhood Trauma and Autoimmune Disease?

 

The Role of Probiotics in Gut Health and Brain Health

just thrive probiotics in Gut health

Tina Anderson, Founder of Just Thrive stops by the show to talk about the role of probiotics in gut health and brain health. Probiotics is like the gardener, its job is to keep the good plants (good bacteria) and get rid of the weeds (bad bacteria). Just Thrive probiotics does this better than any other products on the market because our probiotics arrive alive in the intestine.

The difference with Just Thrive probiotics is that they have this endospore shell around them and that's why we call them spore-based probiotics. This gives them the ability to get through that stomach acid, that gastric system alive.  It is not until they hit the intestines, that the endospore shell comes off and that is when they go into their live vegetative cell state to promote gut and brain health.

Our product Just Calm  is helping communication between the gut and the brain and helping those external stressors that we're faced with by lowering our cortisol levels.

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Bio

Tina Anderson’s journey into the world of health had a unique start and some unusual turns. She began her career as a trial lawyer who specialized in settling cases by bringing both sides together, a personal passion of hers. Once her second child arrived, Tina left that high-stress job behind so she could focus on her family.

Luckily, she was still able to use her considerable legal skills to point her career in a new direction as the in-house counsel for a family pharmaceutical company. But what Tina saw there made her change direction again. Frustrated by the many abuses in the pharmaceutical industry,

Tina turned toward the field of natural health, and found her life’s work. She channeled her energy into learning all she could about disease prevention and good health maintenance. That led her to discover the importance of gut health and how connected and crucial it is for overall health and wellness. To share her discovery with the world, Tina along with her husband created a unique supplement that contains the superior probiotic strains of renowned researcher Dr. Simon Cutting. By promoting gut health and probiotics, Tina shares her passion for wellness, helping others live their best physical and emotional lives.

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How Just Thrive got started

Tina:  I had a very interesting journey. I was I started out in litigation but I wasn't fulfilled in my career. And so, I decided to leave that behind and go into a family pharmaceutical business and had a much better work life balance with my kids. I was able to walk them to school and have more time for prayer, meditation, all of those things. My husband started this company together, we were able to license, probiotic strains, from London University, Dr. Simon a cutting edge world renowned probiotic expert.

And we were able to go into a field that was so impactful, and it was actually impacting health and society and it was really exciting. We knew when you took care of your gut, that everything else starts to fall into place. There was so much research coming out of the Human Microbiome Project was launched by the National Institutes of Health told us more about the gut than we ever knew before, and really told us that the gut is responsible for virtually every aspect of our overall health.

It's hard to find any disease claim that's not associated with some imbalance in our gut health. Very few probiotics on the market, were doing what they needed to do, they were not making that journey to the intestines alive so, we decided to go ahead and launch this product to fill the gap in the market.

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What is the Gut Microbiome

Myrna: Can we step back a little bit and talk about the gut, microbiome, and the blood brain barrier. I know that there are certain things that pass through your gut and cause a whole bunch of disease.  What are, probiotics, and how do they help us in the gut?

Tina: It’s great to start with the fundamentals. Our, microbiome, is the totality of organisms that make up the gut. So, we've got, bacteria, viruses, fungi, you know, parasites, all these different things like make up our the totality of our microbiome. So, all of these microorganisms most of which are bacteria, we are 10 times more bacteria than we are human. We think bacteria is bad, but bacteria is so incredibly beneficial to us, so supportive of our health and our organs.

Less than 1% of bacteria is actually bad.  And so, when we just realized that we have to support our microbiome, in our gut and not kill it off. Constipation, diarrhea, gas and bloating, these are all signs that you have some imbalance going on in your, gut microbiome. But what people are just starting to understand is that it also dictates your, brain health.

  • It dictates your mood, how you're feeling,
  • your sleep,
  • it's dictating your hormone health,
  • it's dictating autoimmune issues, your immune system 80% of our immune system is found in our gut.
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Gut bacteria and leaky gut

Our, gut bacteria, sends signals to our immune cells and tells them okay, there's something going on, you need to start fighting this infection.  So, it's really important that we understand that our immune system would cease to function if we don't have the, gut microbiome, sending signals to our, immune cells.  If you have an, autoimmune disease, it's pretty much guaranteed you have imbalance in your gut, you have a, leaky gut.

We have a double-blind human clinical trial on, leaky gut, that is so profound.  It's important for everybody to understand that it is our gut is dictating all aspects of our overall health. And there is something called the, vagus nerve, that is sends signals from the gut to the brain, and then sends signals from the brain back down to the gut. We all know that feeling you're excited about something and you have butterflies in your stomach, that's the gut brain connection.

We know when we get nervous, you have to go to the bathroom. Same thing the brain is sending signals down to the gut. But what we're also starting to understand is now the gut is sending signals to the brain. So, if you have a healthy balanced, microbiome, they send more calming signals to it. The opposite is also true, if you have an imbalanced gut, it sends signals to your brain that are not so healthy.

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Transform Your Mind Luminary podcast

Brain health and gut health

Understand that it is foundational for our health to focus on our gut. It is where we start. People take multivitamins and they take vitamin C and vitamin D, and those are all important things to be taking. But we need to focus on our, gut health, before we do anything else. And unfortunately, this world we live in is so offensive to the bacteria, we are 10 times more bacterial cells, but we use hand sanitizers and antibacterial soaps to kill off our bacteria.

When you go into the doctor and they say, you have an, autoimmune disease, you need to figure out what it is that's causing this imbalance and this issue and getting to the root cause of it.  So, probiotics,  need to arrive alive in the intestines and make the garden better. So, if you kind of compare your intestinal tract to a garden, you get the weeds which are the bad bacteria and then you have the good plants that are the good bacteria in your gut.

So, the idea is to get those, probiotic strains, into the intestines. The problem with a lot of, probiotics, on the market the vast majority of, probiotics, that are out there have difficulty getting through your stomach acid. That stomach acid is meant to be the gastric barrier. It's meant to keep out things that we don't want in there. So as a result, most, probiotic strains, really have difficulty getting into the intestines and so they're dying by the time they get to the intestines.

And so that was a big problem that we identified and solved with our, Just Thrive probiotics.  So, that's the point of a, probiotic, to make the ecosystem in your gut better and to make it more balanced.  We don't necessarily want to get rid of all the bad bacteria. We just want a better balance in the gut of our good and bad bacteria.

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Just Thrive spore-based probiotics

The difference with, Just Thrive probiotics, is that they have this endospore shell around it and that's why we call them, spore-based probiotics, and they have the ability to get through that stomach acid that gastric system alive.  And it is not until they hit the intestines, that endospore shell comes off and that is when they go into their live vegetative cell state.

Myrna: I understand that because I am taking, Just Thrive probiotics, and I see the difference.  I'm taking the, Just Thrive probiotics, and, Just Calm.

Tina: It is helping get rid of the weeds in the garden. It's helping take those plants that have been stepped down and trampled on and help them thrive and flourish in your gut. And that's why people see such profound results whether it's, becoming more regular, whether it's less gas and bloating, whether it's better mood, better sleep or I'm able to manage my weight better because my gut bacteria is dictating all of those things.

Myrna: Well, yeah, I have noticed that I'm definitely more regular. What are your newest products? What is the difference between probiotics and prebiotics?  Tell us about the newest, Just Thrive, product, Just Calm.

Tina: Yeah, so this is exciting. You know, one of our big core competencies in our company is that we do not produce anything unless it is missing or needed in the market. So, we do not want supplements like vitamin C and vitamin D. Those are all really important nutrients. But there's lots of companies out there doing that great. We are only launching products that are truly missing and needed and researched in the market. So, we just discovered this, probiotic strain.

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Transform Your Mind Podcast Player FM

Phychobiotic the gut friendly probiotic

It is called, psychobiotic. Psychobiotic, is basically gut friendly probiotic that is supporting the gut brain access. So, it's further supporting that communication between the gut and the brain. And so, we know that the gut this is important. I think people are just starting to understand this 90% of our serotonin, which is our happy hormone is produced in our gut for all these years. I feel like psychiatrists have had their hands tied by you know, prescribing, you know, anti-anxiety meds.

90% of our serotonin is produced in our gut. Dopamine is produced in our gut, GABA, which is our calming hormone is produced in our gut. And yet, nobody is talking about that when it comes to, brain health. And so, probiotics, are supporting your serotonin production and your GABA and dopamine but the key with those, psycho biotic, that is found in our product, Just Calm, is that it's actually supporting that, gut brain access.

So, it is helping bring down cortisol levels. We know that cortisol is really disruptive to our gut, it's bringing up we're in that fight or flight response all the time. The problem isn't when you have a, leaky gut, that toxins from your gut seep into your bloodstream and they start to create this inflammatory response and you have this chronic low-grade inflammation, that sending signals up to your brain and so now you have inflammation in your brain. That is the one cause of problems with your, brain health.

Transform your Mind Podcast Index
Transform your Mind Podcast Index

Brain inflammation is caused by external stressors

The other cause of brain inflammation are external stressors. So, we get cut off by traffic, you’ve gotten into a fight with a loved one, whatever it might be that's causing this stress that also causes this inflammation. So, we want to stop both of those things as much as possible or halt as much as possible. We want to get rid of that, leaky gut, and that's what the probiotic is doing. And then those external stressors, we want to be able to manage them better. and by lowering our cortisol.  So, that's what the, Just Calm, product is doing.

It is helping communication between the gut and the brain and helping those external stressors that we're faced with. Intermittent fasting, is just another tool I have in my toolbox. We want to do meditation and deep breathing, whatever it is that calms you down. It's really important whether even if it's changing your lifestyle. There are studies that show that when you, intermittent fasting, it helps increase diversity in the microbiome.

So, the important thing in our gut is we want a diverse, microbiome. We just we don't want one kind of good bacteria. We want lots of different kinds of good bacteria and we were born with a lot of diversity. And we know that, intermittent fasting, helps support diversity.  By starving some of those bacteria it helps them proliferate, which seems counterintuitive, but it's been shown to actually help with supporting your, gut bacteria.

Google Podcast Transform Your Mind
Google Podcast Transform Your Mind

What are prebiotics

Prebiotics, is the fertilizer and the probiotic is like the gardener. The gardener is getting rid of the weeds and helping those plants come back to life. The, prebiotic, is the fertilizer for that garden, so it is feeding the good bacteria in your gut. To really to be defined as a, prebiotic, it needs to only target the beneficial bacteria. So, the good plants in the garden, but the problem is a lot of, prebiotics, it that the actually make a problem worse, by fertilizing the weeds as well as the good plants.

But if you look at our, prebiotic, it's called a precision prebiotic.  We didn't launch a prebiotic for a long time because we could not find prebiotic fibers that only targeted the beneficial bacteria. And so yeah, so our, prebiotic, is only fertilizing the good bacteria in the gut.

We have a product called gut fortified that is helping the mucosal barrier of our gut. We have a health coach on our team, that if anyone have any questions about which products to start with, especially if you have some severe gut dysbiosis and gut issues that you want to deal with, she can help you with a plan of what to do or which products to use.

But I always suggest that people start with a, probiotic, it is foundational for anything else you're doing.  You're eating all these really healthy foods, but if your gut is inflamed, it's not absorbing nutrients. You're taking all these other supplements but if your gut is inflamed, it's not absorbing those nutrients. So, I always suggest people start with the probiotic.  It's our number one selling product.  It's important to stay on it for a couple of months to actually start to notice the difference.

Conclusion

Myrna: How can readers get ahold of your products and also follow you on social media?

Tina: So the best place to find us would be at our website, which is www.just thrivehealth.com. If you use the coupon code TRANSFORM podcast listeners will get 15% off. They can follow us on Instagram, @justthrivehealth. And then if you go to our website, www.justthrivehealth.com you could email us, our one 800 numbers are there, you could contact make an appointment with our product Health coach and she can help you through anything as far as what products you want to start with.

Additional Resources 

http://blog.myhelps.us/8-secrets-to-sexy-total-health/